| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| October 24th, 2009 | 27 | Yes |
Popular Name: 7-[(2S)-2-[(3S)-3-hydroxy-5-phenyl-pentyl]-5-oxo-pyrrolidin-1-yl]heptanoic 7-[(2S)-2-[(3S)-3-hydroxy-5-phen…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 3.57 | 11.16 | -54.5 | 1 | 5 | -1 | 81 | 374.501 | 13 | ↓ |
| Lo Low (pH 4.5-6) | 3.57 | 9.18 | -15.65 | 2 | 5 | 0 | 78 | 375.509 | 13 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PE2R4-2-E | Prostanoid EP4 Receptor (cluster #2 Of 2), Eukaryotic | Eukaryotes | 2705 | 0.29 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PE2R4_RAT | P43114 | Prostanoid EP4 Receptor, Rat | 2705 | 0.29 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| G alpha (s) signalling events | |
| Prostanoid ligand receptors |
