| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| October 24th, 2009 | 30 | Yes |
Popular Name: 4-[3-[(2S)-2-[(3S)-4-(3-chlorophenyl)-3-hydroxy-butyl]-5-oxo-pyrrolidin-1-yl]propyl]benzoic 4-[3-[(2S)-2-[(3S)-4-(3-chloroph…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 4.64 | 12.22 | -60.98 | 1 | 5 | -1 | 81 | 428.936 | 10 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PE2R4-1-E | Prostanoid EP4 Receptor (cluster #1 Of 2), Eukaryotic | Eukaryotes | 42 | 0.34 | Binding ≤ 10μM |
| PE2R4-1-E | Prostanoid EP4 Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 425 | 0.30 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PE2R4_RAT | P43114 | Prostanoid EP4 Receptor, Rat | 42 | 0.34 | Binding ≤ 1μM |
| PE2R4_RAT | P43114 | Prostanoid EP4 Receptor, Rat | 42 | 0.34 | Binding ≤ 10μM |
| PE2R4_RAT | P43114 | Prostanoid EP4 Receptor, Rat | 425 | 0.30 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| G alpha (s) signalling events | |
| Prostanoid ligand receptors |
