| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| October 26th, 2009 | 31 | No |
Popular Name: [(2-chlorophenyl)-dimethyl-BLAHyl]-cyclopropyl-methanone [(2-chlorophenyl)-dimethyl-BLAHy…
None
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 3.28 | 11.21 | -15.74 | 0 | 6 | 0 | 63 | 453.999 | 2 | ↓ |
| Lo Low (pH 4.5-6) | 3.28 | 12.02 | -38.87 | 1 | 6 | 1 | 65 | 455.007 | 2 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PTAFR-1-E | Platelet Activating Factor Receptor (cluster #1 Of 3), Eukaryotic | Eukaryotes | 16 | 0.35 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PTAFR_HUMAN | P25105 | Platelet Activating Factor Receptor, Human | 15.7 | 0.35 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| Class A/1 (Rhodopsin-like receptors) | |
| G alpha (q) signalling events | |
| Interferon gamma signaling |
