Physical Representations
Type
pH range
|
xlogP
|
Des A‑Pol
Apolar desolvation
(kcal/mol)
|
Des Pol
Polar desolvation
(kcal/mol)
|
H Don
H-bond donors
|
H Acc
H-bond acceptors
|
Chg
Net charge
|
tPSA
(Ų)
|
MWT
Molecular weight
(g/mol)
|
RB
Rotatable bonds
|
DL |
Ref
Reference (pH 7)
|
6.35 |
11.31 |
-44.78 |
3 |
5 |
1 |
63 |
469.621 |
7 |
↓
|
Clustered Target Annotations
Code |
Organism Class |
Affinity (nM) |
LE (kcal/mol/atom) |
Type |
PTAFR-2-E |
Platelet Activating Factor Receptor (cluster #2 Of 2), Eukaryotic |
Eukaryotes |
3300 |
0.23 |
Binding ≤ 10μM
|
ChEMBL Target Annotations
Uniprot |
Swissprot |
Affinity (nM) |
LE (kcal/mol/atom) |
Type |
PTAFR_HUMAN |
P25105
|
Platelet Activating Factor Receptor, Human |
3300 |
0.23 |
Binding ≤ 10μM
|
Reactome Annotations from Targets (via Uniprot)
Description |
Species |
Class A/1 (Rhodopsin-like receptors) |
|
G alpha (q) signalling events |
|
Interferon gamma signaling |
|
Rings
-
3,4-dihydro-2H-pyran
-
Piperidine
-
Benzene
-
2,3,4,4a,5,10b-hexahydro-1H-chro…
-
8-(4-phenylbutyl)-2,3,4,4a,5,10b…
No pre-computed analogs available. Try a structural similarity search.