| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| October 26th, 2009 | 30 | No |
Popular Name: 1-decyl-N-(7-methyl-4-oxo-2,3-dihydro-1H-quinolin-8-yl)cyclopentanecarboxamide 1-decyl-N-(7-methyl-4-oxo-2,3-di…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 7.39 | 13.84 | -10.9 | 2 | 4 | 0 | 58 | 412.618 | 11 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| SOAT1-1-E | Acyl Coenzyme A:cholesterol Acyltransferase 1 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 430 | 0.30 | Binding ≤ 10μM |
| SOAT2-1-E | Acyl Coenzyme A:cholesterol Acyltransferase 2 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 430 | 0.30 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| SOAT1_HUMAN | P35610 | Acyl Coenzyme A:cholesterol Acyltransferase 1, Human | 430 | 0.30 | Binding ≤ 1μM |
| SOAT2_HUMAN | O75908 | Acyl Coenzyme A:cholesterol Acyltransferase 2, Human | 430 | 0.30 | Binding ≤ 1μM |
| SOAT1_HUMAN | P35610 | Acyl Coenzyme A:cholesterol Acyltransferase 1, Human | 430 | 0.30 | Binding ≤ 10μM |
| SOAT2_HUMAN | O75908 | Acyl Coenzyme A:cholesterol Acyltransferase 2, Human | 430 | 0.30 | Binding ≤ 10μM |
