| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| November 3rd, 2009 | 28 | Yes |
Popular Name: (2R)-2-(4-cyclopropylsulfonylphenyl)-3-tetrahydropyran-4-yl-N-thiazol-2-yl-propanamide (2R)-2-(4-cyclopropylsulfonylphe…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 2.68 | 7.04 | -20.8 | 1 | 6 | 0 | 85 | 420.556 | 7 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| HXK4-1-E | Hexokinase Type IV (cluster #1 Of 1), Eukaryotic | Eukaryotes | 570 | 0.31 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| HXK4_HUMAN | P35557 | Hexokinase Type IV, Human | 570 | 0.31 | Binding ≤ 1μM |
| HXK4_HUMAN | P35557 | Hexokinase Type IV, Human | 570 | 0.31 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Glucose transport | |
| Regulation of gene expression in beta cells | |
| Regulation of Glucokinase by Glucokinase Regulatory Protein |
