| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| December 9th, 2009 | 20 | Yes |
Popular Name: 3-(3-amino-5-methyl-1,2,4-benzotriazin-7-yl)-4-chloro-phenol 3-(3-amino-5-methyl-1,2,4-benzot…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 3.28 | 4.8 | -8.44 | 3 | 5 | 0 | 85 | 286.722 | 1 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| SRC-1-E | Tyrosine-protein Kinase SRC (cluster #1 Of 3), Eukaryotic | Eukaryotes | 1500 | 0.41 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| SRC_HUMAN | P12931 | Tyrosine-protein Kinase SRC, Human | 1500 | 0.41 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Signaling by ERBB2 |
