| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| September 30th, 2005 | 20 | No |
Popular Name: Tazobactam Tazobactam
Find On: PubMed — Wikipedia — Google
CAS Numbers: 89786-04-9 , [89786-04-9]
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | -3.22 | -6.41 | -56.98 | 0 | 9 | -1 | 125 | 299.288 | 3 | ↓ |
| Note Type | Comments | Provided By |
|---|---|---|
| Therapy | b-lactamase inhibitor | SMDC Pharmakon |
| PUBCHEM_PATENT_ID | EP0331395A1; EP0331395B1; US4562073; US5763603 | IBM Patent Data |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| BLAC-1-B | Beta-lactamase (cluster #1 Of 1), Bacterial | Bacteria | 297 | 0.46 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| BLAC_STAAU | P00807 | Beta-lactamase, Staau | 297 | 0.46 | Binding ≤ 1μM |
| BLAC_STAAU | P00807 | Beta-lactamase, Staau | 2570 | 0.39 | Binding ≤ 10μM |
No pre-computed analogs available. Try a structural similarity search.