| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| January 22nd, 2010 | 25 | Yes |
Popular Name: (2R,3S,4R,5R,6S)-2-(hydroxymethyl)-6-[3-(m-tolylmethyl)phenyl]tetrahydropyran-3,4,5-triol (2R,3S,4R,5R,6S)-2-(hydroxymethy…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 1.96 | 0.28 | -10.39 | 4 | 5 | 0 | 90 | 344.407 | 4 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| SC5A2-1-E | Sodium/glucose Cotransporter 2 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 510 | 0.35 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| SC5A2_HUMAN | P31639 | Sodium/glucose Cotransporter 2, Human | 510 | 0.35 | Binding ≤ 1μM |
| SC5A2_HUMAN | P31639 | Sodium/glucose Cotransporter 2, Human | 510 | 0.35 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Hexose transport | |
| Inositol transporters | |
| Na+-dependent glucose transporters |
