| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| January 22nd, 2010 | 11 | Yes |
Popular Name: 1H-Tetrazole-5-ethanamine, beta-(1-methylethyl)- (9CI) 1H-Tetrazole-5-ethanamine, beta-…
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CAS Number: 758696-64-9
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | -0.75 | -1.06 | -43.94 | 3 | 5 | 0 | 80 | 155.205 | 3 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| CA2D1-3-E | Voltage-gated Calcium Channel Alpha2/delta Subunit 1 (cluster #3 Of 4), Eukaryotic | Eukaryotes | 130 | 0.88 | Binding ≤ 10μM |
| CA2D2-1-E | Voltage-gated Calcium Channel Alpha2/delta Subunit 2 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 130 | 0.88 | Binding ≤ 10μM |
| CA2D3-2-E | Voltage-gated Calcium Channel Alpha2/delta Subunit 3 (cluster #2 Of 2), Eukaryotic | Eukaryotes | 130 | 0.88 | Binding ≤ 10μM |
| CA2D4-2-E | Voltage-gated Calcium Channel Alpha2/delta-4 Subunit (cluster #2 Of 2), Eukaryotic | Eukaryotes | 130 | 0.88 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| CA2D1_HUMAN | P54289 | Voltage-gated Calcium Channel Alpha2/delta Subunit 1, Human | 130 | 0.88 | Binding ≤ 1μM |
| CA2D2_HUMAN | Q9NY47 | Voltage-gated Calcium Channel Alpha2/delta Subunit 2, Human | 130 | 0.88 | Binding ≤ 1μM |
| CA2D3_HUMAN | Q8IZS8 | Voltage-gated Calcium Channel Alpha2/delta Subunit 3, Human | 130 | 0.88 | Binding ≤ 1μM |
| CA2D4_HUMAN | Q7Z3S7 | Voltage-gated Calcium Channel Alpha2/delta-4 Subunit, Human | 130 | 0.88 | Binding ≤ 1μM |
| CA2D1_HUMAN | P54289 | Voltage-gated Calcium Channel Alpha2/delta Subunit 1, Human | 130 | 0.88 | Binding ≤ 10μM |
| CA2D2_HUMAN | Q9NY47 | Voltage-gated Calcium Channel Alpha2/delta Subunit 2, Human | 130 | 0.88 | Binding ≤ 10μM |
| CA2D3_HUMAN | Q8IZS8 | Voltage-gated Calcium Channel Alpha2/delta Subunit 3, Human | 130 | 0.88 | Binding ≤ 10μM |
| CA2D4_HUMAN | Q7Z3S7 | Voltage-gated Calcium Channel Alpha2/delta-4 Subunit, Human | 130 | 0.88 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Adrenaline,noradrenaline inhibits insulin secretion | |
| Depolarization of the Presynaptic Terminal Triggers the Opening of Calcium Chann | |
| Regulation of insulin secretion |
