| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| January 23rd, 2010 | 19 | Yes |
Popular Name: 4-cyclohexyl-N-[2-(1H-imidazol-5-yl)ethyl]butanamide 4-cyclohexyl-N-[2-(1H-imidazol-5…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 2.97 | 7.84 | -40.14 | 3 | 4 | 1 | 59 | 264.393 | 7 | ↓ |
| Ref Reference (pH 7) | 2.97 | 7.86 | -40.12 | 3 | 4 | 1 | 59 | 264.393 | 7 | ↓ |
| Mid Mid (pH 6-8) | 2.97 | 7.37 | -14.04 | 2 | 4 | 0 | 58 | 263.385 | 7 | ↓ |
| Mid Mid (pH 6-8) | 2.97 | 7.35 | -13.4 | 2 | 4 | 0 | 58 | 263.385 | 7 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| HRH3-2-E | Histamine H3 Receptor (cluster #2 Of 2), Eukaryotic | Eukaryotes | 50 | 0.54 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| HRH3_RAT | Q9QYN8 | Histamine H3 Receptor, Rat | 50.1187234 | 0.54 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| G alpha (i) signalling events | |
| Histamine receptors |
