In ZINC since | Heavy atoms | Benign functionality |
---|---|---|
October 3rd, 2005 | 12 | Yes |
Popular Name: 7-Methoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride 7-Methoxy-1,2,3,4-tetrahydroisoq…
Find On: PubMed — Wikipedia — Google
CAS Numbers: 1745-05-7 , 43207-78-9 , [1745-05-7] , [43207-78-9]
1,2,3,4-tetrahydro-7-methoxyisoquinoline
1,2,3,4-Tetrahydro-7-methoxyisoquinoline HCl
1,2,3,4-tetrahydro-7-methoxyisoquinoline hydrochloride
1,2,3,4-tetrahydro-7-methoxyisoquinolinehydrochloride
6-METHOXY-1,2,3,4-TETRAHYDRO-ISOQUINOLINE HYDROCHLORIDE
7-METHOXY-1,2,3,4-TETRAHYDRO-ISOQUINOLINEHYDROCHLORIDE
Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
---|---|---|---|---|---|---|---|---|---|---|
Ref Reference (pH 7) | 1.52 | 3.87 | -42.78 | 2 | 2 | 1 | 26 | 164.228 | 1 | ↓ |
Note Type | Comments | Provided By |
---|---|---|
MP | 234 - 236 | Enamine Building Blocks |
MP | 234...236 | Enamine Building Blocks |
purity | 9.500000000000000e+001 | Enamine Building Blocks Enamine Building Blocks |
Purity | 95% | Fluorochem |
Purity | >95% | Matrix Scientific |
Warnings | IRRITANT | Matrix Scientific |
Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
ADA2A-3-E | Alpha-2a Adrenergic Receptor (cluster #3 Of 4), Eukaryotic | Eukaryotes | 470 | 0.74 | Binding ≤ 10μM |
ADA2B-1-E | Alpha-2b Adrenergic Receptor (cluster #1 Of 4), Eukaryotic | Eukaryotes | 470 | 0.74 | Binding ≤ 10μM |
ADA2C-3-E | Alpha-2c Adrenergic Receptor (cluster #3 Of 4), Eukaryotic | Eukaryotes | 470 | 0.74 | Binding ≤ 10μM |
Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
ADA2A_RAT | P22909 | Alpha-2a Adrenergic Receptor, Rat | 470 | 0.74 | Binding ≤ 1μM |
ADA2B_RAT | P19328 | Alpha-2b Adrenergic Receptor, Rat | 470 | 0.74 | Binding ≤ 1μM |
ADA2C_RAT | P22086 | Alpha-2c Adrenergic Receptor, Rat | 470 | 0.74 | Binding ≤ 1μM |
ADA2A_RAT | P22909 | Alpha-2a Adrenergic Receptor, Rat | 470 | 0.74 | Binding ≤ 10μM |
ADA2B_RAT | P19328 | Alpha-2b Adrenergic Receptor, Rat | 470 | 0.74 | Binding ≤ 10μM |
ADA2C_RAT | P22086 | Alpha-2c Adrenergic Receptor, Rat | 470 | 0.74 | Binding ≤ 10μM |
Description | Species |
---|---|
Adrenaline signalling through Alpha-2 adrenergic receptor | |
Adrenaline,noradrenaline inhibits insulin secretion | |
Adrenoceptors | |
G alpha (i) signalling events | |
G alpha (z) signalling events |