| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| October 18th, 2005 | 42 | No |
Popular Name: BRD-K70241288-001-01-1 BRD-K70241288-001-01-1
None
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 4.13 | 9.93 | -70.8 | 4 | 10 | 0 | 139 | 567.694 | 10 | ↓ |
| Hi High (pH 8-9.5) | 4.13 | 8.66 | -48.51 | 3 | 10 | -1 | 134 | 566.686 | 10 | ↓ |
| Lo Low (pH 4.5-6) | 4.13 | 9.93 | -46.97 | 5 | 10 | 1 | 141 | 568.702 | 10 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| GHRHR-1-E | Growth Hormone-releasing Hormone Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 3 | 0.28 | Functional ≤ 10μM |
| Z50597-1-O | Rattus Norvegicus (cluster #1 Of 12), Other | Other | 3 | 0.28 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| GHRHR_RAT | Q02644 | Growth Hormone-releasing Hormone Receptor, Rat | 3 | 0.28 | Functional ≤ 10μM |
| Z50597 | Z50597 | Rattus Norvegicus | 3 | 0.28 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| G alpha (s) signalling events | |
| Glucagon-type ligand receptors |
