UCSF

ZINC03933534

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Substance Information

In ZINC since Heavy atoms Benign functionality
October 20th, 2005 38 No

Popular Name: JNJ-5207787 JNJ-5207787

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Download: MOL2 SDF SMILES Flexibase

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 5.35 18.11 -43.97 1 6 1 69 511.69 7 ↓

Activity (Go SEA)

Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
NPY2R-1-E Neuropeptide Y Receptor Type 2 (cluster #1 Of 1), Eukaryotic Eukaryotes 100 0.26 Binding ≤ 10μM
NPY2R-1-E Neuropeptide Y Receptor Type 2 (cluster #1 Of 1), Eukaryotic Eukaryotes 63 0.27 Functional ≤ 10μM
ChEMBL Target Annotations
Uniprot Swissprot Description Affinity (nM) LE (kcal/mol/atom) Type
NPY2R_HUMAN P49146 Neuropeptide Y Receptor Type 2, Human 100 0.26 Binding ≤ 1μM
NPY2R_HUMAN P49146 Neuropeptide Y Receptor Type 2, Human 100 0.26 Binding ≤ 10μM
NPY2R_HUMAN P49146 Neuropeptide Y Receptor Type 2, Human 63.0957344 0.27 Functional ≤ 10μM

Reactome Annotations from Targets (via Uniprot)

Description Species
G alpha (i) signalling events
Peptide ligand-binding receptors

Analogs ( Draw Identity 99% 90% 80% 70% )

No pre-computed analogs available. Try a structural similarity search.