In ZINC since | Heavy atoms | Benign functionality |
---|---|---|
October 21st, 2005 | 27 | Yes |
Popular Name: N-(6-benzyloxy-3-hydroxy-2,2-dimethyl-chroman-4-yl)-N-methyl-methanesulfonamide N-(6-benzyloxy-3-hydroxy-2,2-dim…
Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
---|---|---|---|---|---|---|---|---|---|---|
Ref Reference (pH 7) | 2.96 | -4.75 | -15.96 | 1 | 6 | 0 | 76 | 391.489 | 5 | ↓ |
Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
KCNE1-1-E | Voltage-gated Potassium Channel Beta Subunit Mink (cluster #1 Of 2), Eukaryotic | Eukaryotes | 200 | 0.35 | Binding ≤ 10μM |
KCNQ1-1-E | Voltage-gated Potassium Channel Subunit Kv7.1 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 200 | 0.35 | Binding ≤ 10μM |
Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
KCNE1_HUMAN | P15382 | Voltage-gated Potassium Channel Beta Subunit Mink, Human | 200 | 0.35 | Binding ≤ 1μM |
KCNQ1_HUMAN | P51787 | Voltage-gated Potassium Channel Subunit Kv7.1, Human | 200 | 0.35 | Binding ≤ 1μM |
KCNE1_HUMAN | P15382 | Voltage-gated Potassium Channel Beta Subunit Mink, Human | 200 | 0.35 | Binding ≤ 10μM |
KCNQ1_HUMAN | P51787 | Voltage-gated Potassium Channel Subunit Kv7.1, Human | 200 | 0.35 | Binding ≤ 10μM |
Description | Species |
---|---|
Voltage gated Potassium channels |