| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| October 24th, 2005 | 15 | Yes |
Popular Name: 10012-47-2; 2-(dimethylamino)ethyl 4-aminobenzoate; nsc25247 10012-47-2; 2-(dimethylamino)eth…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 1.21 | 5.35 | -37.95 | 3 | 4 | 1 | 57 | 209.269 | 5 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PHLP2-2-E | PH Domain Leucine-rich Repeat-containing Protein Phosphatase 2 (cluster #2 Of 2), Eukaryotic | Eukaryotes | 5000 | 0.49 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PHLP2_HUMAN | Q6ZVD8 | PH Domain Leucine-rich Repeat-containing Protein Phosphatase 2, Human | 5000 | 0.49 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Negative regulation of the PI3K/AKT network |
