| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| October 25th, 2005 | 38 | No |
6,10-Diaza-3(1,3)8,(1,4)-dibenzena-1,5(1,4)-diquinolinacyclodecaphane; C13783; UCL 1684
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | -2.52 | 16.38 | -67.76 | 2 | 4 | 2 | 32 | 494.642 | 0 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| KCNN1-1-E | Small Conductance Calcium-activated Potassium Channel Protein 1 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 3 | 0.31 | Binding ≤ 10μM |
| KCNN3-1-E | Small Conductance Calcium-activated Potassium Channel Protein 3 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 3 | 0.31 | Binding ≤ 10μM |
| KCNN1-1-E | Small Conductance Calcium-activated Potassium Channel Protein 1 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 3 | 0.31 | Functional ≤ 10μM |
| KCNN2-1-E | Small Conductance Calcium-activated Potassium Channel Protein 2 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 3 | 0.31 | Functional ≤ 10μM |
| KCNN3-1-E | Small Conductance Calcium-activated Potassium Channel Protein 3 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 3 | 0.31 | Functional ≤ 10μM |
| Z50597-1-O | Rattus Norvegicus (cluster #1 Of 12), Other | Other | 3 | 0.31 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| KCNN1_HUMAN | Q92952 | Small Conductance Calcium-activated Potassium Channel Protein 1, Human | 3 | 0.31 | Binding ≤ 1μM |
| KCNN3_RAT | P70605 | Small Conductance Calcium-activated Potassium Channel Protein 3, Rat | 1.8 | 0.32 | Binding ≤ 1μM |
| KCNN1_HUMAN | Q92952 | Small Conductance Calcium-activated Potassium Channel Protein 1, Human | 3 | 0.31 | Binding ≤ 10μM |
| KCNN3_RAT | P70605 | Small Conductance Calcium-activated Potassium Channel Protein 3, Rat | 1.8 | 0.32 | Binding ≤ 10μM |
| Z50597 | Z50597 | Rattus Norvegicus | 3 | 0.31 | Functional ≤ 10μM |
| KCNN1_RAT | P70606 | Small Conductance Calcium-activated Potassium Channel Protein 1, Rat | 3 | 0.31 | Functional ≤ 10μM |
| KCNN2_RAT | P70604 | Small Conductance Calcium-activated Potassium Channel Protein 2, Rat | 3 | 0.31 | Functional ≤ 10μM |
| KCNN3_RAT | P70605 | Small Conductance Calcium-activated Potassium Channel Protein 3, Rat | 3 | 0.31 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| Ca2+ activated K+ channels |
