| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| October 25th, 2005 | 21 | Yes |
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | -3.26 | 5.76 | -187.82 | 2 | 9 | -3 | 162 | 301.275 | 9 | ↓ |
| Lo Low (pH 4.5-6) | -3.26 | 3.85 | -115.47 | 3 | 9 | -2 | 159 | 302.283 | 9 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| FOLH1-1-E | Glutamate Carboxypeptidase II (cluster #1 Of 2), Eukaryotic | Eukaryotes | 1 | 0.60 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| FOLH1_HUMAN | Q04609 | Glutamate Carboxypeptidase II, Human | 0.75 | 0.61 | Binding ≤ 1μM |
| FOLH1_HUMAN | Q04609 | Glutamate Carboxypeptidase II, Human | 0.75 | 0.61 | Binding ≤ 10μM |
