| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| October 28th, 2005 | 28 | No |
Popular Name: MEDROXYPROGESTERONE ACETATE MEDROXYPROGESTERONE ACETATE
Find On: PubMed — Wikipedia — Google
CAS Numbers: 71-58-9, 520-85-4 [medrox , 71-58-9, 520-85-4 [medroxyprogesterone]
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 4.04 | 11.8 | -16.68 | 0 | 4 | 0 | 60 | 386.532 | 3 | ↓ |
| Note Type | Comments | Provided By |
|---|---|---|
| Therapy | contraceptive | SMDC Pharmakon |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PRGR-1-E | Progesterone Receptor (cluster #1 Of 3), Eukaryotic | Eukaryotes | 11 | 0.40 | Binding ≤ 10μM |
| PRGR-2-E | Progesterone Receptor (cluster #2 Of 2), Eukaryotic | Eukaryotes | 1 | 0.45 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PRGR_HUMAN | P06401 | Progesterone Receptor, Human | 10.8 | 0.40 | Binding ≤ 1μM |
| PRGR_HUMAN | P06401 | Progesterone Receptor, Human | 10.8 | 0.40 | Binding ≤ 10μM |
| PRGR_HUMAN | P06401 | Progesterone Receptor, Human | 0.12 | 0.50 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| Nuclear Receptor transcription pathway | |
| Nuclear signaling by ERBB4 |
