| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| April 6th, 2010 | 16 | Yes |
Popular Name: glycine, N-(3H-imidazo[4,5-c]pyridin-4-ylcarbonyl)- glycine, N-(3H-imidazo[4,5-c]pyr…
Find On: PubMed — Wikipedia — Google
CAS Number: 1078167-98-2
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | -1.90 | 1.74 | -57.56 | 2 | 7 | -1 | 111 | 219.18 | 3 | ↓ |
| Mid Mid (pH 6-8) | -1.90 | 1.23 | -93.54 | 1 | 7 | -2 | 109 | 218.172 | 3 | ↓ |
| Mid Mid (pH 6-8) | -1.90 | -0.26 | -11.85 | 3 | 7 | 0 | 108 | 220.188 | 3 | ↓ |
| Lo Low (pH 4.5-6) | -1.90 | 2.21 | -58.36 | 3 | 7 | 0 | 112 | 220.188 | 3 | ↓ |
| Lo Low (pH 4.5-6) | -1.90 | 2.19 | -66.51 | 3 | 7 | 0 | 112 | 220.188 | 3 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| EGLN1-1-E | Egl Nine Homolog 1 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 2820 | 0.49 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| EGLN1_HUMAN | Q9GZT9 | Egl Nine Homolog 1, Human | 2820 | 0.49 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha |
No pre-computed analogs available. Try a structural similarity search.