| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| April 12th, 2010 | 19 | Yes |
Popular Name: 5-chloro-N-(5-chloro-2-hydroxy-phenyl)-2-hydroxy-benzamide 5-chloro-N-(5-chloro-2-hydroxy-p…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 4.36 | 3.23 | -9.17 | 3 | 4 | 0 | 70 | 298.125 | 2 | ↓ |
| Hi High (pH 8-9.5) | 4.36 | 4.23 | -48.24 | 2 | 4 | -1 | 72 | 297.117 | 2 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| KCMA1-1-E | Calcium-activated Potassium Channel Subunit Alpha-1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 372 | 0.47 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| KCMA1_HUMAN | Q12791 | Large Conductance Calcium-activated Potassium Channel Subfamily M Alpha Member 1 Isoform B, Human | 371.535229 | 0.47 | Binding ≤ 1μM |
| KCMA1_HUMAN | Q12791 | Large Conductance Calcium-activated Potassium Channel Subfamily M Alpha Member 1 Isoform B, Human | 371.535229 | 0.47 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Ca2+ activated K+ channels | |
| cGMP effects |
