| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| November 6th, 2005 | 15 | No |
Popular Name: 4-styryl-2-pyrimidinethiol 4-styryl-2-pyrimidinethiol
Find On: PubMed — Wikipedia — Google
CAS Number: 1243314-15-9
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 2.62 | 7.73 | -25.05 | 1 | 2 | 0 | 29 | 214.293 | 2 | ↓ |
| Hi High (pH 8-9.5) | 3.34 | 7.39 | -52.15 | 0 | 2 | -1 | 26 | 213.285 | 2 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| GRM4-1-E | Metabotropic Glutamate Receptor 4 (cluster #1 Of 3), Eukaryotic | Eukaryotes | 7800 | 0.48 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| GRM4_HUMAN | Q14833 | Metabotropic Glutamate Receptor 4, Human | 7800 | 0.48 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Class C/3 (Metabotropic glutamate/pheromone receptors) | |
| G alpha (i) signalling events |
