| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| April 13th, 2010 | 30 | Yes |
Popular Name: 3-methyl-N-[(1S)-1-methyl-2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)ethyl]benzamide 3-methyl-N-[(1S)-1-methyl-2-(4-o…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 3.06 | 9.22 | -45.89 | 3 | 6 | 1 | 66 | 407.538 | 5 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PLD1-1-E | Phospholipase D1 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 3400 | 0.26 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PLD1_HUMAN | Q13393 | Phospholipase D1, Human | 3400 | 0.26 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Role of phospholipids in phagocytosis | |
| Synthesis of PA | |
| Synthesis of PG |
