| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| April 13th, 2010 | 25 | Yes |
Popular Name: 2-amino-5-(2-methoxyphenoxy)-N-(4-methylthiazol-2-yl)benzamide 2-amino-5-(2-methoxyphenoxy)-N-(…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 3.08 | 6.27 | -10.55 | 3 | 6 | 0 | 86 | 355.419 | 5 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| HXK4-1-E | Hexokinase Type IV (cluster #1 Of 1), Eukaryotic | Eukaryotes | 410 | 0.36 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| HXK4_HUMAN | P35557 | Hexokinase Type IV, Human | 120 | 0.39 | Binding ≤ 1μM |
| HXK4_HUMAN | P35557 | Hexokinase Type IV, Human | 120 | 0.39 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Glucose transport | |
| Regulation of gene expression in beta cells | |
| Regulation of Glucokinase by Glucokinase Regulatory Protein |
