| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| April 13th, 2010 | 24 | Yes |
Popular Name: 2-amino-5-(4-fluorophenoxy)-N-(4-methylthiazol-2-yl)benzamide 2-amino-5-(4-fluorophenoxy)-N-(4…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 3.43 | 6.45 | -8.38 | 3 | 5 | 0 | 77 | 343.383 | 4 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| HXK4-1-E | Hexokinase Type IV (cluster #1 Of 1), Eukaryotic | Eukaryotes | 400 | 0.37 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| HXK4_HUMAN | P35557 | Hexokinase Type IV, Human | 400 | 0.37 | Binding ≤ 1μM |
| HXK4_HUMAN | P35557 | Hexokinase Type IV, Human | 1700 | 0.34 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Glucose transport | |
| Regulation of gene expression in beta cells | |
| Regulation of Glucokinase by Glucokinase Regulatory Protein |
