In ZINC since | Heavy atoms | Benign functionality |
---|---|---|
April 13th, 2010 | 25 | Yes |
Popular Name: 3-(dimethylamino)-5-[3-[3-(dimethylamino)-5-hydroxy-phenoxy]propoxy]phenol 3-(dimethylamino)-5-[3-[3-(dimet…
Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
---|---|---|---|---|---|---|---|---|---|---|
Ref Reference (pH 7) | 3.05 | 3.2 | -10.27 | 2 | 6 | 0 | 65 | 346.427 | 8 | ↓ |
Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
ACES-10-E | Acetylcholinesterase (cluster #10 Of 12), Eukaryotic | Eukaryotes | 1905 | 0.32 | Binding ≤ 10μM |
Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
ACES_BOVIN | P23795 | Acetylcholinesterase, Bovin | 1905 | 0.32 | Binding ≤ 10μM |
Description | Species |
---|---|
Neurotransmitter Clearance In The Synaptic Cleft | |
Synthesis of PC |