| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| April 13th, 2010 | 26 | Yes |
Popular Name: 1'-(5,6-difluoro-1H-benzimidazol-2-yl)spiro[isobenzofuran-3,4'-piperidine]-1-one 1'-(5,6-difluoro-1H-benzimidazol…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 3.78 | 11.7 | -13.92 | 1 | 5 | 0 | 58 | 355.344 | 1 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| NPY5R-1-E | Neuropeptide Y Receptor Type 5 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 5 | 0.45 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| NPY5R_HUMAN | Q15761 | Neuropeptide Y Receptor Type 5, Human | 4.8 | 0.45 | Binding ≤ 1μM |
| NPY5R_HUMAN | Q15761 | Neuropeptide Y Receptor Type 5, Human | 4.8 | 0.45 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| G alpha (i) signalling events | |
| Peptide ligand-binding receptors |
