| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| April 14th, 2010 | 33 | Yes |
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 4.55 | 12.54 | -54.92 | 3 | 6 | 1 | 71 | 463.989 | 5 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PLD1-1-E | Phospholipase D1 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 46 | 0.31 | Binding ≤ 10μM |
| PLD2-1-E | Phospholipase D2 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 933 | 0.26 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PLD1_HUMAN | Q13393 | Phospholipase D1, Human | 11 | 0.34 | Binding ≤ 1μM |
| PLD2_HUMAN | O14939 | Phospholipase D2, Human | 933 | 0.26 | Binding ≤ 1μM |
| PLD1_HUMAN | Q13393 | Phospholipase D1, Human | 11 | 0.34 | Binding ≤ 10μM |
| PLD2_HUMAN | O14939 | Phospholipase D2, Human | 1800 | 0.24 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Role of phospholipids in phagocytosis | |
| Synthesis of PA | |
| Synthesis of PG |
