| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| April 14th, 2010 | 15 | Yes |
Popular Name: {2-[4-(trifluoromethyl)phenyl]cyclopropyl}methanamine hydrochloride {2-[4-(trifluoromethyl)phenyl]cy…
Find On: PubMed — Wikipedia — Google
CAS Numbers: 1267449-56-8 , 1354952-92-3
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 2.22 | 5.65 | -47.61 | 3 | 1 | 1 | 28 | 216.226 | 3 | ↓ |
| Note Type | Comments | Provided By |
|---|---|---|
| MP | 192 - 194 | Enamine Building Blocks |
| MP | 192...194 | Enamine Building Blocks |
| purity | 9.500000000000000e+001 | Enamine Building Blocks Enamine Building Blocks |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| 5HT2C-2-E | 5-hydroxytryptamine Receptor 2C (cluster #2 Of 2), Eukaryotic | Eukaryotes | 779 | 0.57 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| 5HT2C_HUMAN | P28335 | Serotonin 2c (5-HT2c) Receptor, Human | 779 | 0.57 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| G alpha (q) signalling events | |
| Serotonin receptors |
