In ZINC since | Heavy atoms | Benign functionality |
---|---|---|
April 14th, 2010 | 32 | Yes |
Popular Name: (4S)-1'-[(4-chlorophenyl)methylsulfonyl]-4-phenyl-spiro[chromane-2,4'-piperidine] (4S)-1'-[(4-chlorophenyl)methyls…
Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
---|---|---|---|---|---|---|---|---|---|---|
Ref Reference (pH 7) | 5.78 | 12.44 | -14.45 | 0 | 4 | 0 | 47 | 468.018 | 4 | ↓ |
Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
OPRD-1-E | Delta Opioid Receptor (cluster #1 Of 3), Eukaryotic | Eukaryotes | 500 | 0.28 | Binding ≤ 10μM |
Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
OPRD_HUMAN | P41143 | Delta Opioid Receptor, Human | 500 | 0.28 | Binding ≤ 1μM |
OPRD_HUMAN | P41143 | Delta Opioid Receptor, Human | 500 | 0.28 | Binding ≤ 10μM |
Description | Species |
---|---|
G alpha (i) signalling events | |
Peptide ligand-binding receptors |