UCSF

ZINC04099172

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Substance Information

In ZINC since Heavy atoms Benign functionality
November 7th, 2005 30 No

Popular Name: N-FORMYL-MET-LEU-PHE N-FORMYL-MET-LEU-PHE

Find On: PubMed — Wikipedia — Google

CAS Number: 59880-97-6

Download: MOL2 SDF SMILES Flexibase

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -0.30 8.9 -61.02 3 8 -1 127 436.554 13 ↓

Vendor Notes

Note Type Comments Provided By
UniProt Database Links CHIPS_STAA3; CHIPS_STAA8; CHIPS_STAAE; CHIPS_STAAN; CHIPS_STAAR; FPR1_GORGO; FPR1_HUMAN; FPR1_MACMU; FPR1_MOUSE; FPR1_PANTR; FPR1_PONPY; FPR1_RABIT; FPR2_GORGO; FPR2_HUMAN; FPR2_MACMU; FPR2_MOUSE; FPR2_PANTR; FPR2_PONPY; FPR3_GORGO; FPR3_HUMAN; FPR3_MACMU ChEBI
Reactome Database Links REACT_15538; REACT_21390; REACT_22239; REACT_22289 ChEBI

Activity (Go SEA)

Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
FPR1-1-E Formyl Peptide Receptor 1 (cluster #1 Of 1), Eukaryotic Eukaryotes 42 0.34 Binding ≤ 10μM
FPR1-1-E Formyl Peptide Receptor 1 (cluster #1 Of 2), Eukaryotic Eukaryotes 20 0.36 Functional ≤ 10μM
Q6L5J4-1-E FML2_HUMAN (cluster #1 Of 1), Eukaryotic Eukaryotes 1900 0.27 Functional ≤ 10μM
ChEMBL Target Annotations
Uniprot Swissprot Description Affinity (nM) LE (kcal/mol/atom) Type
FPR1_HUMAN P21462 Formyl Peptide Receptor 1, Human 20 0.36 Binding ≤ 1μM
FPR1_HUMAN P21462 Formyl Peptide Receptor 1, Human 20 0.36 Binding ≤ 10μM
Q6L5J4_HUMAN Q6L5J4 FML2_HUMAN, Human 1900 0.27 Functional ≤ 10μM
FPR1_HUMAN P21462 Formyl Peptide Receptor 1, Human 10 0.37 Functional ≤ 10μM

Direct Reactome Annotations (via ChEBI)

Description Species
Formyl peptide receptors bind formyl peptides and many other ligands
G alpha (i) signalling events

Reactome Annotations from Targets (via Uniprot)

Description Species
Formyl peptide receptors bind formyl peptides and many other ligands
G alpha (i) signalling events

Analogs ( Draw Identity 99% 90% 80% 70% )