| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| November 8th, 2005 | 21 | No |
Popular Name: 5-(3-phenoxybenzyl)-1,3-thiazolane-2,4-dione 5-(3-phenoxybenzyl)-1,3-thiazola…
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CAS Number: 262844-57-5
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 3.19 | 6.48 | -8.15 | 1 | 4 | 0 | 55 | 299.351 | 4 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| FFAR1-1-E | Free Fatty Acid Receptor 1 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 4700 | 0.36 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| FFAR1_HUMAN | O14842 | Free Fatty Acid Receptor 1, Human | 4700 | 0.36 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion | |
| Free fatty acid receptors | |
| G alpha (q) signalling events | |
| Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) | |
| Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polyp |
