| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| November 11th, 2005 | 33 | Yes |
Popular Name: 2-methyl-7-[[(6-methyl-2-pyridinyl)amino](3,4,5-trimethoxyphenyl)methyl]-8-quinolinol 2-methyl-7-[[(6-methyl-2-pyridin…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 3.50 | -1.13 | -42.03 | 3 | 7 | 1 | 86 | 446.527 | 7 | ↓ |
| Lo Low (pH 4.5-6) | 3.50 | -0.98 | -84.61 | 4 | 7 | 2 | 88 | 447.535 | 7 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| SC5A2-1-E | Sodium/glucose Cotransporter 2 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 5920 | 0.22 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| SC5A2_HUMAN | P31639 | Sodium/glucose Cotransporter 2, Human | 5920 | 0.22 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Hexose transport | |
| Inositol transporters | |
| Na+-dependent glucose transporters |
