| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| November 15th, 2005 | 17 | Yes |
Popular Name: 6-bromo-4-(piperazin-1-yl)quinazoline hydrochloride 6-bromo-4-(piperazin-1-yl)quinaz…
Find On: PubMed — Wikipedia — Google
CAS Numbers: 1177356-94-3 , 205259-86-5
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 1.84 | -4.31 | -45.84 | 2 | 4 | 1 | 45 | 294.176 | 1 | ↓ |
| Note Type | Comments | Provided By |
|---|---|---|
| purity | 9.500000000000000e+001 | Enamine Building Blocks Enamine Building Blocks |
| MP | 99 - 101 | Enamine Building Blocks |
| MP | 99...101 | Enamine Building Blocks |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| HD-1-E | Huntingtin (cluster #1 Of 1), Eukaryotic | Eukaryotes | 2740 | 0.46 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| HD_HUMAN | P42858 | Huntingtin, Human | 2740 | 0.46 | Binding ≤ 10μM |
