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Quick Search ZINC ID or SMILES

Synonyms (42)
Vendors (29)
Annotations (25)
Representations (2)
Notes (14)
Targets (4)
Clustered (2)
Reactome (1)
Rings (0)
Analogs (12)

ZINC04228242

4228242

Draw Identity 99% 90% 80% 70%

Substance Information

In ZINC since	Heavy atoms	Benign functionality
November 15^th, 2005	23	No

Popular Name: Disodium 5'-Inosinate Disodium 5'-Inosinate

Find On: PubMed — Wikipedia — Google

CAS Numbers: 131-99-7 , 20813-76-7 , 24939-03-5 , 352195-40-5 , 4691-65-0 , [131-99-7] , [3387-37-9] , [4691-65-0] , [4961-65-3]

Other Names:

"Inosine 5'-monophosphate, 98%"

'Inosine-5''-monophosphoric acid disodium salt'

(rI(n).r(C(12)U)n); 5'-Inosinic acid, homopolymer, complex with 5'-cytidylic acid polymer with 5'-uridylic acid (1:1); Atvogen; C10H13N4O8P.C9H13N2O9P.C9H14N3O8P; DRG-0001; LS-174734; POLYI-POLYC12U; Poly I-Poly C (C12,U); Poly I:Poly C12U; ampligen; mism

131-99-7; 5'-IMP; 5'-Inosinate; 5'-Inosine monophosphate; 5'-Inosinic acid; C00130; IMP; Inosine 5'-monophosphate; Inosine 5'-phosphate; Inosine monophosphate; Inosinic acid

131-99-7; 5'-IMP; 5'-inosinate; 5'-inosine monophosphate; 5'-inosinic acid; IMP; inosinate; inosine 5'-monophosphate; inosine 5'-phosphate; inosine monophosphate; inosine-5'-phosphate; ribosylhypoxanthine monophosphate

5'-Imp disodium salt; 5'-Inosinic acid, disodium salt; CCRIS 6560; DISODIUM INOSINATE; Disodium 5'-inosinate; Disodium inosine 5'-monophosphate; Disodium inosine 5'-phosphate; Disodium inosine-5'-monophosphate; EINECS 225-146-4; FEMA No. 3669; IMP disodiu

5'-IMP; 5'-Inosinate; 5'-Inosine monophosphate; 5'-Inosinic acid; IMP; Inosine 5'-monophosphate; Inosine 5'-phosphate; Inosine Monophosphate; Inosine-5'-monophosphate

5'-IMP; 5'-INOSINIC ACID; 5'-Inosinate; 5'-Inosine monophosphate; BRN 0630517; IMP; Inosine 5'-Monophosphoric acid; Inosine 5'-monophosphate; Inosine 5'-phosphate; Inosine monophosphate; Inosine-5'-monophosphoric acid; Inosinic acid; bmse000175

5'-IMP; 5'-Inosinic acid; BRN 0630517; EINECS 205-045-1; IMP; Inosine 5'-Monophosphoric acid; Inosine 5'-monophosphate; Inosine 5'-phosphate; Inosine monophosphate; Inosine-5'-monophosphoric acid; Inosinic acid; LS-84009

5'-IMP;5'-Inosinate;5'-Inosine monophosphate;5'-Inosinic acid;IMP;Inosine 5'-monophosphate;Inosine 5'-phosphate;Inosine Monophosphate;Inosine-5'-monophosphate

5'-INOSINIC ACID DISODIUM SALT HYDRATE

5'-Inosinic acid, homopolymer, complex with 5'-cytidylic acid homopolymer (1:1); 5'-Inosinic acid, polymers, complex with 5'-cytidylic acid polymers (1:1); LS-118090; NSC 123233; NSC-120949; PI:C; Poly C poly I; Poly I-C; Poly I:poly C; Poly rI:poly rC; P

5'-INOSINICACIDDISODIUMSALTHYDRATE

Calcium 5-inosinate

CHEBI:43475; CHEBI:43418; CHEBI:43524; CHEBI:43528; CHEBI:43611; CHEBI:5849; CHEBI:43563; CHEBI:47501; CHEBI:12057; CHEBI:13372; CHEBI:12063; CHEBI:14457; CHEBI:13373; CHEBI:19271

Disodium 5'-Inosinate Hydrate

Disodium 5'-ribonucleotide; LS-73932; Ribotide; disodium 5'-O-phosphonatoinosine

hypoxanthosine 5'-monophosphate; inosine-5'-monophosphate; ribosylhypoxanthine monophosphate

IMP; IMP dianion; inosine 5'-phosphate; inosine 5'-phosphate dianion; inosine 5'-phosphate(2-)

INOSINE 5'-MONOPHOSPHATE DISODIUM SALT

Inosine 5'-Monophosphate Disodium Salt Hydrate

Inosine 5'-monophosphate, disodium salt hydrate, 97%

Inosine-5'-monophosphate

Inosine-5'-monophosphate sodium salt

Inosine-5'-monophosphate sodium salt, 97%+

Inosine-5'-monophosphoric acid disodium salt

L-Lysine, homopolymer, complex with 5'-cytidylic acid, homopolymer and 5'-inosinic acid, homopolymer (1:1:1); LS-88445; Poly (ICL)

Polycytidylic acid

Polyinosinic acid Polycytidylic acid

Polyinosinic acid-polycytidylic acid

[(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-oxo-1H-purin-9-yl)oxolan-2-yl]methoxyphosphonic acid

SMILES:

Download: MOL2 SDF SMILES Flexibase

Annotations

Vendors

Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	-2.49	-2.22	-152.4	3	12	-2	186	346.192	4	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	-2.49	-3.38	-61.47	4	12	-1	183	347.2	4	↓ MOL2 SDF SMILES Flexibase

Vendor Notes

Note Type	Comments	Provided By
Mp [°C]	175	Acros Organics
UniProt Database Links	5NTC_BOVIN; 5NTC_CHICK; 5NTC_DICDI; 5NTC_HUMAN; 5NTC_MOUSE; 5NTC_PONAB; 5NTC_XENLA; 5NTC_XENTR; 5NTD_PSEAE; AMPD1_CHICK; AMPD1_HUMAN; AMPD1_MOUSE; AMPD1_RABIT; AMPD1_RAT; AMPD2_HUMAN; AMPD2_MOUSE; AMPD2_RAT; AMPD3_HUMAN; AMPD3_MOUSE; AMPD3_RAT; AMPD_ARATH	ChEBI
Purity	95%	Fluorochem
PUBCHEM_PATENT_ID	EP0030327A2; EP0076489A2; EP0083261A1; EP0093401A1; EP0203381A1; EP0238672A1; EP0242831A1; EP0242831B1; EP0249435A2; EP0249435B1; EP0256654A2; EP0256654B1; EP0273660B1; EP0282989A2; EP0282989B1; EP0286303A1; EP0286303B1; EP0286838B2; EP0292171A2; EP030190	IBM Patent Data
Patent Database Links	EP1806134; US2007218112	ChEBI
H phrase	H373: May cause damage to organs through prolonged or repeated exposure	Acros Organics
H phrase	H373: May cause damage to organs through prolonged or repeated exposure; H361f: Suspected of damaging fertility	Acros Organics
P phrase	P281: Use personal protective equipment as required	Acros Organics
P phrase	P281: Use personal protective equipment as required; P260: Do not breathe dust/fume/gas/mist/vapors/spray	Acros Organics
R phrase	R33: Danger of cumulative effects.	Acros Organics
R phrase	R33: Danger of cumulative effects.; R62: Possible risk of impaired fertility.	Acros Organics
Reactome Database Links	REACT_120749; REACT_120992; REACT_1336; REACT_1444; REACT_1488; REACT_150277; REACT_150396; REACT_163645; REACT_1719; REACT_1972; REACT_2012; REACT_21383; REACT_263; REACT_700; REACT_849	ChEBI
S phrase	S36/37: Wear suitable protective clothing and gloves.	Acros Organics
Hazard	XN: Harmful	Acros Organics

Activity (Go SEA)

Clustered Target Annotations
Code	Description	Organism Class	Affinity (nM)	LE (kcal/mol/atom)	Type
IMDH1-1-E	Inosine-5'-monophosphate Dehydrogenase 1 (cluster #1 Of 1), Eukaryotic	Eukaryotes	250	0.40	Binding ≤ 10μM
IMDH2-1-E	Inosine-5'-monophosphate Dehydrogenase 2 (cluster #1 Of 2), Eukaryotic	Eukaryotes	250	0.40	Binding ≤ 10μM

ChEMBL Target Annotations
Uniprot	Swissprot	Description	Affinity (nM)	LE (kcal/mol/atom)	Type
IMDH1_HUMAN	P20839	Inosine-5'-monophosphate Dehydrogenase 1, Human	250	0.40	Binding ≤ 1μM
IMDH2_HUMAN	P12268	Inosine-5'-monophosphate Dehydrogenase 2, Human	250	0.40	Binding ≤ 1μM
IMDH1_HUMAN	P20839	Inosine-5'-monophosphate Dehydrogenase 1, Human	250	0.40	Binding ≤ 10μM
IMDH2_HUMAN	P12268	Inosine-5'-monophosphate Dehydrogenase 2, Human	250	0.40	Binding ≤ 10μM

Direct Reactome Annotations (via ChEBI)

Description	Species
Abacavir metabolism	Taeniopygia guttata Homo sapiens Oryza sativa Mus musculus Danio rerio Drosophila melanogaster Arabidopsis thaliana Dictyostelium discoideum Rattus norvegicus Caenorhabditis elegans Canis familiaris Bos taurus Sus scrofa Gallus gallus Xenopus tropicalis
De novo synthesis of AMP	Gallus gallus
De novo synthesis of GMP	Gallus gallus
De novo synthesis of IMP	Gallus gallus
Metabolism of nucleotides	Caenorhabditis elegans Homo sapiens Bos taurus Danio rerio Gallus gallus Taeniopygia guttata Dictyostelium discoideum Drosophila melanogaster Arabidopsis thaliana Sus scrofa Schizosaccharomyces pombe Canis familiaris Mus musculus Saccharomyces cerevisiae Rattus norvegicus Plasmodium falciparum Oryza sativa
Phosphate bond hydrolysis by NUDT proteins	Sus scrofa Danio rerio Bos taurus Mus musculus Homo sapiens Canis familiaris Rattus norvegicus Xenopus tropicalis
Purine catabolism	Danio rerio Caenorhabditis elegans Mus musculus Canis familiaris Gallus gallus Homo sapiens Drosophila melanogaster Taeniopygia guttata Oryza sativa Sus scrofa Xenopus tropicalis Dictyostelium discoideum Arabidopsis thaliana Bos taurus Rattus norvegicus
Purine ribonucleoside monophosphate biosynthesis	Gallus gallus Canis familiaris Homo sapiens Sus scrofa Taeniopygia guttata Mus musculus Xenopus tropicalis Arabidopsis thaliana Dictyostelium discoideum Schizosaccharomyces pombe Plasmodium falciparum Rattus norvegicus Drosophila melanogaster Danio rerio Oryza sativa Bos taurus Caenorhabditis elegans Saccharomyces cerevisiae
Purine salvage	Gallus gallus Schizosaccharomyces pombe Xenopus tropicalis Homo sapiens Sus scrofa Taeniopygia guttata Bos taurus Saccharomyces cerevisiae Dictyostelium discoideum Arabidopsis thaliana Drosophila melanogaster Oryza sativa Caenorhabditis elegans Rattus norvegicus Danio rerio Plasmodium falciparum Canis familiaris Mus musculus
Scavenging by Class A Receptors	Sus scrofa Canis familiaris Mus musculus Rattus norvegicus Bos taurus Drosophila melanogaster Homo sapiens Danio rerio Xenopus tropicalis
Urate synthesis	Gallus gallus

Reactome Annotations from Targets (via Uniprot)

Description	Species
Purine ribonucleoside monophosphate biosynthesis	Homo sapiens (IMDH2_HUMAN)

Analogs ( Draw Identity 99% 90% 80% 70% )

Synonyms (42)
Vendors (29)
Annotations (25)
Representations (2)
Notes (14)
Targets (4)
Clustered (2)
Reactome (1)
Rings (0)
Analogs (12)