| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| May 5th, 2010 | 44 | No |
Popular Name: DNC013810 DNC013810
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 0.95 | 8.59 | -58.28 | 6 | 10 | 1 | 147 | 600.74 | 12 | ↓ |
| Mid Mid (pH 6-8) | 0.95 | 8.27 | -25.73 | 5 | 10 | 0 | 145 | 599.732 | 12 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| OPRM-1-E | Mu-type Opioid Receptor (cluster #1 Of 4), Eukaryotic | Eukaryotes | 273 | 0.21 | Binding ≤ 10μM |
| OPRD-1-E | Delta Opioid Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 2723 | 0.18 | Functional ≤ 10μM |
| Q8CGM4-1-E | Mu-opioid Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1810 | 0.18 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| OPRM_RAT | P33535 | Mu Opioid Receptor, Rat | 272.7 | 0.21 | Binding ≤ 1μM |
| OPRM_RAT | P33535 | Mu Opioid Receptor, Rat | 272.7 | 0.21 | Binding ≤ 10μM |
| OPRD_MOUSE | P32300 | Delta Opioid Receptor, Mouse | 2723 | 0.18 | Functional ≤ 10μM |
| Q8CGM4_CAVPO | Q8CGM4 | Mu-opioid Receptor, Guinea Pig | 1810 | 0.18 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| G alpha (i) signalling events | |
| G-protein activation | |
| Opioid Signalling | |
| Peptide ligand-binding receptors |
