UCSF

ZINC43015507

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Substance Information

In ZINC since Heavy atoms Benign functionality
May 6th, 2010 29 Yes

Popular Name: GSK 650394 GSK 650394

Find On: PubMed — Wikipedia — Google

CAS Number: 890842-28-1

Other Names:

GSK650394

MFCD12828779

N/A

Download: MOL2 SDF SMILES Flexibase

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 5.81 14.67 -59.57 1 4 -1 69 381.455 4 ↓

Vendor Notes

Note Type Comments Provided By
Target Others Selleck Chemicals

Activity (Go SEA)

Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
SGK1-1-E Serine/threonine-protein Kinase Sgk1 (cluster #1 Of 2), Eukaryotic Eukaryotes 580 0.30 Binding ≤ 10μM
ChEMBL Target Annotations
Uniprot Swissprot Description Affinity (nM) LE (kcal/mol/atom) Type
SGK1_HUMAN O00141 Serine/threonine-protein Kinase Sgk1, Human 13 0.38 Binding ≤ 1μM
SGK1_HUMAN O00141 Serine/threonine-protein Kinase Sgk1, Human 13 0.38 Binding ≤ 10μM

Reactome Annotations from Targets (via Uniprot)

Description Species
Stimuli-sensing channels

Analogs ( Draw Identity 99% 90% 80% 70% )

No pre-computed analogs available. Try a structural similarity search.