In ZINC since | Heavy atoms | Benign functionality |
---|---|---|
May 6th, 2010 | 33 | No |
None
Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
---|---|---|---|---|---|---|---|---|---|---|
Ref Reference (pH 7) | -1.00 | 4.1 | -51.6 | 6 | 11 | 0 | 173 | 474.543 | 10 | ↓ |
Hi High (pH 8-9.5) | -1.00 | 3.82 | -53.87 | 5 | 11 | -1 | 171 | 473.535 | 10 | ↓ |
Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
DNM3B-1-E | DNA (cytosine-5)-methyltransferase 3B (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1000 | 0.25 | Binding ≤ 10μM |
Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
DNM3B_HUMAN | Q9UBC3 | DNA (cytosine-5)-methyltransferase 3B, Human | 1000 | 0.25 | Binding ≤ 1μM |
DNM3B_HUMAN | Q9UBC3 | DNA (cytosine-5)-methyltransferase 3B, Human | 1000 | 0.25 | Binding ≤ 10μM |
Description | Species |
---|---|
NoRC negatively regulates rRNA expression | |
PRC2 methylates histones and DNA |