| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| May 7th, 2010 | 22 | Yes |
Popular Name: 1-(6-chloroimidazo[2,1-b]thiazol-5-yl)sulfonylpyrrolo[3,2-b]pyridin-6-amine 1-(6-chloroimidazo[2,1-b]thiazol…
None
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 2.05 | 2.76 | -16.94 | 2 | 7 | 0 | 95 | 353.816 | 2 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| MET-1-E | Hepatocyte Growth Factor Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 580 | 0.40 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| MET_HUMAN | P08581 | Hepatocyte Growth Factor Receptor, Human | 10 | 0.51 | Binding ≤ 1μM |
| MET_HUMAN | P08581 | Hepatocyte Growth Factor Receptor, Human | 10 | 0.51 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Sema4D mediated inhibition of cell attachment and migration |
