In ZINC since | Heavy atoms | Benign functionality |
---|---|---|
May 7th, 2010 | 34 | Yes |
Popular Name: 4-[[1-(1,3-benzodioxol-5-ylmethyl)-4-piperidyl]methyl]-N-[(1S)-1-cyclohexylethyl]benzamide 4-[[1-(1,3-benzodioxol-5-ylmethy…
Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
---|---|---|---|---|---|---|---|---|---|---|
Ref Reference (pH 7) | 6.02 | 14.18 | -50.7 | 2 | 5 | 1 | 52 | 463.642 | 7 | ↓ |
Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
MCHR1-1-E | Melanin-concentrating Hormone Receptor 1 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 3567 | 0.22 | Binding ≤ 10μM |
Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
MCHR1_HUMAN | Q99705 | Melanin-concentrating Hormone Receptor 1, Human | 3567 | 0.22 | Binding ≤ 10μM |
Description | Species |
---|---|
G alpha (i) signalling events | |
G alpha (q) signalling events | |
Peptide ligand-binding receptors |