| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| November 20th, 2005 | 24 | No |
Popular Name: 2-({2-[(2-chloro-6-phenoxybenzyl)amino]-2-oxoethyl}sulfanyl)acetic acid 2-({2-[(2-chloro-6-phenoxybenzyl…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 2.92 | 8.86 | -54.42 | 1 | 5 | -1 | 78 | 364.83 | 8 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| FABP4-3-E | Fatty Acid Binding Protein Adipocyte (cluster #3 Of 3), Eukaryotic | Eukaryotes | 3100 | 0.32 | Binding ≤ 10μM |
| FABPH-1-E | Fatty Acid Binding Protein Muscle (cluster #1 Of 3), Eukaryotic | Eukaryotes | 1900 | 0.33 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| FABP4_HUMAN | P15090 | Fatty Acid Binding Protein Adipocyte, Human | 3100 | 0.32 | Binding ≤ 10μM |
| FABPH_HUMAN | P05413 | Fatty Acid Binding Protein Muscle, Human | 1900 | 0.33 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis | |
| Transcriptional regulation of white adipocyte differentiation |
