| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| November 27th, 2005 | 19 | Yes |
Popular Name: 4-amino-2-methyl-6-(6-methyl-1,3-benzoxazol-2-yl)phenol 4-amino-2-methyl-6-(6-methyl-1,3…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 3.23 | -3.34 | -10.41 | 3 | 4 | 0 | 72 | 254.289 | 1 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| KS6A3-1-E | Ribosomal Protein S6 Kinase Alpha 3 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1380 | 0.43 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| KS6A3_HUMAN | P51812 | Ribosomal Protein S6 Kinase Alpha 3, Human | 1380 | 0.43 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| CREB phosphorylation | |
| CREB phosphorylation through the activation of Ras | |
| ERK/MAPK targets | |
| Gastrin-CREB signalling pathway via PKC and MAPK | |
| Recycling pathway of L1 | |
| RSK activation | |
| Senescence-Associated Secretory Phenotype (SASP) |
