| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| May 24th, 2010 | 43 | No |
Popular Name: DNC014811 DNC014811
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 8.35 | 10.29 | -16.3 | 5 | 7 | 0 | 127 | 582.693 | 12 | ↓ |
| Hi High (pH 8-9.5) | 8.35 | 11.98 | -117.38 | 3 | 7 | -2 | 133 | 580.677 | 12 | ↓ |
| Mid Mid (pH 6-8) | 8.35 | 11.02 | -41.88 | 4 | 7 | -1 | 130 | 581.685 | 12 | ↓ |
| Mid Mid (pH 6-8) | 8.35 | 11.25 | -48.91 | 4 | 7 | -1 | 130 | 581.685 | 12 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| DPOLB-3-E | DNA Polymerase Beta (cluster #3 Of 3), Eukaryotic | Eukaryotes | 4300 | 0.17 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| DPOLB_RAT | P06766 | DNA Polymerase Beta, Rat | 1200 | 0.19 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Base-free sugar-phosphate removal via the single-nucleotide replacement pathway | |
| Removal of DNA patch containing abasic residue | |
| Resolution of AP sites via the single-nucleotide replacement pathway |
