| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| May 24th, 2010 | 25 | No |
Popular Name: Methyl Arachidonyl Fluorophosphonate Methyl Arachidonyl Fluorophospho…
Find On: PubMed — Wikipedia — Google
CAS Number: 188404-10-6
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 8.80 | 15.96 | -6.54 | 0 | 2 | 0 | 26 | 378.553 | 20 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| CNR1-2-E | Cannabinoid CB1 Receptor (cluster #2 Of 5), Eukaryotic | Eukaryotes | 20 | 0.43 | Binding ≤ 10μM |
| FAAH1-3-E | Anandamide Amidohydrolase (cluster #3 Of 7), Eukaryotic | Eukaryotes | 0 | 0.00 | Binding ≤ 10μM |
| MGLL-1-E | Monoglyceride Lipase (cluster #1 Of 7), Eukaryotic | Eukaryotes | 2 | 0.49 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| FAAH1_MOUSE | O08914 | Anandamide Amidohydrolase, Mouse | 0.1 | 0.56 | Binding ≤ 1μM |
| CNR1_MOUSE | P47746 | Cannabinoid CB1 Receptor, Mouse | 20 | 0.43 | Binding ≤ 1μM |
| MGLL_MOUSE | O35678 | Monoglyceride Lipase, Mouse | 2.2 | 0.48 | Binding ≤ 1μM |
| FAAH1_MOUSE | O08914 | Anandamide Amidohydrolase, Mouse | 0.1 | 0.56 | Binding ≤ 10μM |
| CNR1_MOUSE | P47746 | Cannabinoid CB1 Receptor, Mouse | 20 | 0.43 | Binding ≤ 10μM |
| MGLL_MOUSE | O35678 | Monoglyceride Lipase, Mouse | 2.2 | 0.48 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Acyl chain remodeling of DAG and TAG | |
| Arachidonate production from DAG | |
| Class A/1 (Rhodopsin-like receptors) | |
| G alpha (i) signalling events | |
| Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
No pre-computed analogs available. Try a structural similarity search.