| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| May 24th, 2010 | 19 | No |
Popular Name: DNC009162 DNC009162
3,4,5-tribromo-2-(2', 4'-dibromo-phenoxy)phenol
None
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 7.00 | 8.18 | -4.63 | 1 | 2 | 0 | 29 | 580.69 | 2 | ↓ |
| Mid Mid (pH 6-8) | 7.00 | 9.09 | -32.45 | 0 | 2 | -1 | 32 | 579.682 | 2 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| LOX15-3-E | Arachidonate 15-lipoxygenase (cluster #3 Of 5), Eukaryotic | Eukaryotes | 7400 | 0.38 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| LOX15_HUMAN | P16050 | Arachidonate 15-lipoxygenase, Human | 7400 | 0.38 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Synthesis of 12-eicosatetraenoic acid derivatives | |
| Synthesis of 15-eicosatetraenoic acid derivatives | |
| Synthesis of Leukotrienes (LT) and Eoxins (EX) |
