| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| December 25th, 2005 | 25 | No |
Popular Name: N-(3-methoxyphenyl)-3-nitro-4-pyrrolidin-1-yl-benzamide N-(3-methoxyphenyl)-3-nitro-4-py…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 3.25 | 9.09 | -19.13 | 1 | 7 | 0 | 87 | 341.367 | 5 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| TAAR1-1-E | Trace Amine-associated Receptor 1 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 13 | 0.44 | Binding ≤ 10μM |
| TAAR1-1-E | Trace Amine-associated Receptor 1 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 17 | 0.44 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| TAAR1_MOUSE | Q923Y8 | Trace Amine-associated Receptor1, Mouse | 13 | 0.44 | Binding ≤ 1μM |
| TAAR1_MOUSE | Q923Y8 | Trace Amine-associated Receptor1, Mouse | 13 | 0.44 | Binding ≤ 10μM |
| TAAR1_MOUSE | Q923Y8 | Trace Amine-associated Receptor1, Mouse | 17 | 0.44 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| Amine ligand-binding receptors | |
| G alpha (s) signalling events |
