UCSF

ZINC04696706

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Substance Information

In ZINC since Heavy atoms Benign functionality
December 30th, 2005 23 Yes

Popular Name: DNC008275 DNC008275

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Download: MOL2 SDF SMILES Flexibase

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 5.03 3.96 -7.04 0 2 0 26 302.373 5 ↓

Activity (Go SEA)

Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
KCNN4-1-E Intermediate Conductance Calcium-activated Potassium Channel Protein 4 (cluster #1 Of 2), Eukaryotic Eukaryotes 330 0.39 Binding ≤ 10μM
ChEMBL Target Annotations
Uniprot Swissprot Description Affinity (nM) LE (kcal/mol/atom) Type
KCNN4_HUMAN O15554 Intermediate Conductance Calcium-activated Potassium Channel Protein 4, Human 330 0.39 Binding ≤ 1μM
KCNN4_HUMAN O15554 Intermediate Conductance Calcium-activated Potassium Channel Protein 4, Human 330 0.39 Binding ≤ 10μM

Reactome Annotations from Targets (via Uniprot)

Description Species
Ca2+ activated K+ channels

Analogs ( Draw Identity 99% 90% 80% 70% )

No pre-computed analogs available. Try a structural similarity search.