| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| January 8th, 2006 | 21 | No |
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 2.78 | 8.15 | -9.16 | 0 | 4 | 0 | 56 | 276.295 | 3 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| DAPK1-1-E | Death-associated Protein Kinase 1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1000 | 0.40 | Binding ≤ 10μM |
| DAPK3-1-E | Death-associated Protein Kinase 3 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 1000 | 0.40 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| DAPK1_HUMAN | P53355 | Death-associated Protein Kinase 1, Human | 1000 | 0.40 | Binding ≤ 1μM |
| DAPK3_HUMAN | O43293 | Death-associated Protein Kinase 3, Human | 1000 | 0.40 | Binding ≤ 1μM |
| DAPK1_HUMAN | P53355 | Death-associated Protein Kinase 1, Human | 1000 | 0.40 | Binding ≤ 10μM |
| DAPK3_HUMAN | O43293 | Death-associated Protein Kinase 3, Human | 1000 | 0.40 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Role of DCC in regulating apoptosis |
