| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| September 23rd, 2010 | 20 | Yes |
Popular Name: N-(3-chloro-2-fluoro-phenyl)-6-fluoro-quinazolin-4-amine N-(3-chloro-2-fluoro-phenyl)-6-f…
None
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 3.57 | 9.54 | -6.44 | 1 | 3 | 0 | 38 | 291.688 | 2 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| GRM5-1-E | Metabotropic Glutamate Receptor 5 (cluster #1 Of 5), Eukaryotic | Eukaryotes | 3720 | 0.38 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| GRM5_RAT | P31424 | Metabotropic Glutamate Receptor 5, Rat | 3720 | 0.38 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| Class C/3 (Metabotropic glutamate/pheromone receptors) | |
| G alpha (q) signalling events |
