| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| September 23rd, 2010 | 16 | No |
Popular Name: (2S)-2-amino-4-[hydroxy-(4-hydroxy-4-oxo-butyl)phosphoryl]butanoic (2S)-2-amino-4-[hydroxy-(4-hydro…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | -3.92 | 2.41 | -129.83 | 3 | 7 | -2 | 148 | 251.175 | 8 | ↓ |
| Hi High (pH 8-9.5) | -3.92 | 2.12 | -173.62 | 2 | 7 | -3 | 146 | 250.167 | 8 | ↓ |
| Lo Low (pH 4.5-6) | -3.92 | 0.42 | -72.97 | 4 | 7 | -1 | 145 | 252.183 | 8 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| GRM4-1-E | Metabotropic Glutamate Receptor 4 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 8500 | 0.44 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| GRM4_RAT | P31423 | Metabotropic Glutamate Receptor 4, Rat | 8500 | 0.44 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| Class C/3 (Metabotropic glutamate/pheromone receptors) | |
| G alpha (i) signalling events |
